Spreng. Thymoquinone (5) was further identified as a nonpolar ingredient from the hexane extract of P. amboinicus to suppress the expression of lipopolysaccharide-induced tumor necrosis factor-alpha (TNF-α). USA.gov. Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Plectranthus hadiensis (Forssk.) Evaluating the prolonged effects of medicinal plant extracts used in humans is useful Copyright © 2014 Elsevier Ltd. All rights reserved. 22(5):1766–1772. several chemical constituents and had shown various biological properties. The genus Plectranthus in India and its chemistry. This has led to its uncontrolled harvest from the wild leading to the risk of extinction. Keywords: The gas-chromatography analysis of the ethyl acetate extract of Plectranthus amboinicus revealed the presence of seven different compounds. View larger version Accordingly, we continued to isolate the compounds from subfraction PO2 by high performance liquid chromatography (HPLC). 2017;17(1):462. Epub 2020 Oct 26. Plectranthus amboinicus is an attractive, evergreen perennial plant with lemon-scented, thick, succulent, sprawling stems and fleshy leaves; it can grow 50 - 100cm tall[238. Chem Biodivers. Methods: The leaves of Plectranthus amboinicus, (Lour.) Non-Volatile Chemical Constituents of P. amboinicus A total of 30 non-volatile constituents have been identified from P. amboinicus according to our literature survey [17,48]. Chemical composition and Toxicological evaluation of the aqueous leaf extracts of Plectranthus amboinicus Lour. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Journal of Essential Oil Bearing Plants: Vol. Spreng. Antimicrobial Activities P. amboinicus extract, from crude extract to an essential oil, contains innumerable biological constituents owing to its chemical diversity.  |  The study aimed to estimate antifungal property and chemical composition of the three medicinal plants Cymbopogon citratus (lemongrass), Cajanus cajan (pigeon pea) and Plectranthus amboinicus (thick leaf thyme) leaves collected from the coastal areas of Guyana. Present study describes the comprehensive pharmacognostic aspects of P.hadiensis and P. amboinicus by means of physical and chemical yield parameters. J Ethnopharmacol. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin, Flavour and Fragrance Journal, 10.1002/ffj.1608, 21, 3, (472-479), (2006). Essential oil of Plectranthus amboinicus was studied for its chemical composition and larvicidal potential against the malarial vector mosquito Anopheles stephensi. Some of them are commonly known as boldo and present taxonomic similarities and several synonymies, with antidyspeptic, analgesic and digestive actions. Essential Oil from Archipelago of Comoros. NLM Damanik R, Wahlqvist ML, Wattanapenpaiboon N. 2006. Plectranthus amboinicus (Lour.) This review is an effort to compile all the information reported on its phytochemical and pharmacological activities. The composition of the essential oil of the leaves of Plectranthus neochilus was analyzed by GC and GC/MS. In vivo study of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus (Lour.) Spreng (Lamiaceae). Therefore, the present study was undertaken to assess the chemical composition and toxicity profile of the aqueous leaf extract of P. amboinicus. Nevertheless, it is known that the chemical constituents of EO-Pa differed from those of the collected samples from diverse geographical places, in which more than 70 different constituents have been described. eCollection 2019. Spreng. Major chemical components and content (%) of the essential oil in Plectranthus amboinicus under inoculation or not with Claroideoglomus etunicatum and Rhizophagus clarus under low and high addition (20 or 200 mg dm −3 of soil) of P in the substrate. Fig 2 Leaf of Plectranthus amboinicus Lour. Publication Author Bown. Ten components were characterized representing 94.0% of the total components detected. The chemical constituents 1–5 of Plectranthus amboinicus and synthetic analogs 8a–d inhibit the binding of AP-1 to its consensus DNA sequence and suppress the expression of lipopolysaccharide-induced TNF-α. In this oil, carvacrol constitutes the major compound … Plant phytochemicals possess antimicrobial activity against a wide range of bacteria, yeast and mold, but vary in quantity and quality depending on the bioactive constituents [3,4,53]. Morphological, anatomical Thin Layer Chromatographic profiles, essential oil content and composition were carried out according to the established protocols. In the present work, the chemical characterization, antimicrobial, antiparasitic, and cytotoxic properties of the essential oil from Plectranthus amboinicus (Lour.) 2020 Jul 2;15(7):e0235416. Flowers Flowers are shortly pedicelled, 3 mm long, pale purplish in dense whorls at distant intervals in a long slender raceme. Essential Oil from Archipelago of Comoros. Karpooravalli is a potential remedy for anxiety and stress. Phytochemical composition and larvicidal activity of essential oils from herbal plants. Totally 26 compounds were identified by GC and GC-MS. 91 Accesses. The chemical composition of the volatile oil of P. amboinicus growing in different areas had been subjected to various Bioorg Med Chem. The variations ca… Among them, PAEA-fraction 60 contained a major active bioactive compound, hexadecanoic acid, methyl ester (270.0). Lactagogue effects of Torbangun, a Bataknese traditional cuisine. Photo Gallery. mg/g extract) was predominant, followed by caeic acid (.mg/g extract), rutin (. Other parts of the plant contain an essential oil known as thymol. Metrics details. (2012). Ashaari NS, Ab Rahim MH, Sabri S, Lai KS, Song AA, Abdul Rahim R, Wan Abdullah WMAN, Ong Abdullah J. PLoS One. 7. Plectranthus amboinicus (Lour.) We then synthesized 2-alkylidenyl-4-cyclopentene-1,3-diones as the designed biomimetics of thymoquinone, and found that compounds 8a, 8b and 8d were more potent TNF-α inhibitors. This is a preview of subscription content, log in to check access. Tungmunnithum D, Garros L, Drouet S, Renouard S, Lainé E, Hano C. Plants (Basel). Crystal Engineering Construction of Caffeic Acid Derivatives with Potential Applications in Pharmaceuticals and Degradable Polymeric Materials. Objective: The present investigation was undertaken to explore the possible mechanisms of Plectranthus amboinicus leaf extract in alloxan-induced diabetic rats. 2019 Feb 27;8(3):50. doi: 10.3390/plants8030050. 4, … Spreng. Table 3 Constituents and Contents of PO2 Fraction From Leaf Essential Oil of Plectranthus amboinicus. Spreng … Chen Y-S, Yu H-M, Shie J-J, Cheng T-JR, Wu C-Y, Fang J-M, Wong C-H. 2014. 15, No. Plectranthus amboinicus (Lour.) Gastrointestinal Diseases. Place and Duration of Study: Plants were gathered along the East Coast of … Epub 2014 Feb 3. Journal of Essential Oil Bearing Plants… Essential oil was isolated from the leaves of Plectranthus amboinicus by hydrodistillation and analyzed using both gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). ... Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus. several chemical constituents and had shown various biological properties. View larger version Accordingly, we continued to isolate the compounds from subfraction PO2 by high performance liquid chromatography (HPLC). Start Over. Title Encyclopaedia of Herbs and their Uses. ex Sprenger. Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity. In the present work, the chemical characterization, antimicrobial, antiparasitic, and cytotoxic properties of the essential oil from Plectranthus amboinicus (Lour.) Phytochemical profiling and biological activity of Plectranthus amboinicus (Lour.) We then synthesized 2-alkylidenyl-4-cyclopentene-1,3-diones as the designed biomimetics of thymoquinone, and found that compounds 8a, 8b and 8d were more potent TNF-α inhibitors. Spreng and its main compound carvacrol were studied. The various constituents of the essential oil Parasitol Res. EFFECTS OF NACL ON GROWTH, ESSENTIAL OIL AND CHEMICAL COMPOSITION OF PLECTRANTHUS AMBOINICUS Hoda Sany1, Hussein A.H. Said-Al Ahl2*, Rosario P. Mauro3 and Tess Astatkie4 1Department of Botany (Plant Physiology Section), Faculty of Agriculture, Cairo University, Giza, Egypt. Maxia A, Sanna C, Frau MA, Piras A, Karchuli MS, Kasture V. Molecules. mg/gextract),quercetin(.mg/gextract),and p-coumaricacid(.  |  Another analysis obtained thymol (41.3%), carvacrol (13.25%), 1,8-cineole (5.45%), eugenol (4.40%), caryophyllene (4.20%), terpinolene (3.75%), α-pinene (3.20%), β-pinene (2.50%), methyl eugenol (2.10%), and β-phellandrene(1.90%). Spreng. Phytochemical constituents isolated from Indian species of the genus Plectranthus reported up to 2009 are compiled. and essential oil producing capability [8,9]. Chemical Constituents of the Leaves of Plectranthus amboinicus. Citation in PubAg 36; Full Text 4; Journal. is a perennial herb belonging to the family Lamiaceae which occurs naturally throughout the tropics and warm regions of Africa, Asia and Australia. 2*Medicinal and Aromatic Plants Research Department, National Research Centre, 33 El Bohouth St., Wang Z, Flores Q, Guo H, Trevizo R, Zhang X, Wang S. CrystEngComm. Please enable it to take advantage of the complete set of features! Plectranthus amboinicus, otherwise called as Coleus amboinicus or Coleus aromaticus commonly known as country borage is a dicotyledonous plant of Lamiaceae family [4, 5]. Gurgel AP, da Silva JG, Grangeiro AR, Oliveira DC, Lima CM, da Silva AC, Oliveira RA, Souza IA. It is native to Southern and Eastern Africa. and Coleus amboinicus Lour.) The stem of Indian borage (Plectranthus amboinicus) was found to be an antioxidant rich fraction as evaluated by in vitro models such as DPPH free radical scavenging, reducing power assay, superoxide anion radical scavenging, and total antioxidant capacity. Twenty-one components were identified in the oil by gas chromatography coupled with a mass spectrometric detector. Chemical structures of the main constituents identified in the essential oils of the three investigated Plectranthus species. Among the major phenolics, rosmarinic acid (. Chemical Constituents. P. amboinicus extract, from crude extract to an essential oil, contains innumerable biological constituents owing to its chemical diversity. GCMS analysis revealed the presence of 11 chemical compounds constituting 97.6% of the total extract composition. eCollection 2020. It is large succulent aromatic perennial herb, shrubby below, hispidly villous or tomentose. Thymoquinone (5) was further identified as a nonpolar ingredient from the hexane extract of P. amboinicus to suppress the expression of lipopolysaccharide-induced tumor necrosis factor-alpha (TNF-α). Plectranthus amboinicus (Loureiro) Sprengel is one of the most documented species in the family Lamiaceae. 2014 Apr;100:132-40. doi: 10.1016/j.phytochem.2014.01.002. Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Plectranthus amboinicus (Loureiro) Sprengel is a therapeutically valued herb highly sought by various industries. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Ayushvedah provides all the informations about parnayavani - Coleus amboinicus Benth., Plectranthus amboinicus (Lour.) Spreng / Savina Asiimwe, Anna-Karin Borg- Karlsson, Muhammad Azeem, Kamatenesi Maud Mugisha, Agnes Namutebi and Ndukui James Gakunga / International Journal of Pharmaceutical Science Invention, Volume 3 Issue 2, February 2014, PP.19-27 Spreng (synonyms include Plectranthus aromaticus Roxb., Coleus aromaticus Benth. BMC Complement Altern Med. Planta. DeepDyve is the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. 2010;107:1275–8. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. In India, the genus Plectranthus is found in all the habitats and altitudes, particularly in the Himalaya, the Southern Ghats, and the Nilgiri region. is a perennial herb with a 3-10 years life span, and it is native to Indonesia[1]. Study Design: Experiment based study. The chemical constituents 1 – 5 of Plectranthus amboinicus and synthetic analogs 8a – d inhibit the binding of AP-1 to its consensus DNA sequence and suppress the expression of lipopolysaccharide-induced TNF-α. COVID-19 is an emerging, rapidly evolving situation. Epub 2009 Jul 14. Spreng. Novel chemical constituents with anti-inflammatory activity from the leaves of Sesbania aculeata. We use cookies to help provide and enhance our service and tailor content and ads. Flowers References ↑ Chemical constituents Phytochemical screening of the ethanolic extract of the leaves was carried out according to the qualitative phytochemical screening tests to evaluate the presence of its chemical constituents such as alkaloid, flavonoid, saponin, triterpenoid, steroid and phenolic. Huang HT, Lin CC, Kuo TC, Chen SJ, Huang RN. Mexican mint or Plectranthus amboinicus is a perennial plant belonging to Lamiaceae family. Chemical Composition of The Essential Oil and Aqueous Extract of Plectranthus amboinicus R. Vera 1, J. M. Mondon 2, J. C. Pieribattesti 1. Commonly seen growing in areas. The extract also exhibited antiplatelet aggregation ability, antibacterial activity, and antiproliferative effect against cancer cell lines: Caco-2, HCT-15, and MCF-7. The present review is an attempt to generate interest among the masses regarding its immense potential in preventing and treating the several diseases. and Plectranthus amboinicus (Lour.) (2012). Essential oil of Plectranthus amboinicus was studied for its chemical composition and larvicidal potential against the malarial vector mosquito Anopheles stephensi. This herb has therapeutic and nutritional properties attributed to its natural phytochemical compounds which are highly valued in the pharmaceutical industry. Some of them are commonly known as boldo and present taxonomic similarities and several synonymies, with antidyspeptic, analgesic and digestive actions. A … Schweinf. The details of these phytocompounds are … Senthilkumar A, Venkatesalu V. Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (lour.) NCI CPTC Antibody Characterization Program. By continuing you agree to the use of cookies. In traditional system of medicine, Plectranthus amboinicus is used in the treatment of renal calculi, malarial fever, hepatopathy, chronic asthma, hiccough, helminthiasis and epilepsy. 2-Alkylidenyl-4-cyclopentene-1,3-diones; Anti-inflammation; Plectranthus amboinicus; Rosmarinic acid; Thymoquinone. The principle constituents include linalool (50.3 %), nerol acetate (11.6%), geranyl acetate (11.7 %) and carvacrol (14.3%). Totally 26 compounds were identified by GC and GC-MS. Ten components were characterized representing 94.0% of the total components detected. These non-volatile chemical components included phenolic acids, flavonoids, monoterpene hydrocarbons, sesquiterpene hydrocarbons, oxygenated monoterpenes and esters. This herb has therapeutic and nutritional properties attributed to its natural phytochemical compounds which are highly valued in the pharmaceutical industry. Download : Download full-size image Objectives: to evaluate the antioxidant and cytotoxic activities of Plectranthus amboinicus, (Lour.) This study demonstrates that compounds 1-4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. Front Pharmacol. Clipboard, Search History, and several other advanced features are temporarily unavailable. Phytochemical evaluation of the extract revealed the occurrence of total phenolic… is a perennial herb belonging to the family Lamiaceae which occurs naturally throughout the tropics and warm regions of Africa, Asia and Australia. These non-volatile chemical components included phenolic acids, flavonoids, monoterpene hydrocarbons, sesquiterpene hydrocarbons, oxygenated monoterpenes and esters. The major chemical compounds were carvacrol (28.65%) followed by thymol (21.66%), α-humulene (9.67%), undecanal (8.29%), γ-terpinene (7.76%), ρ-cymene (6.46%), … mg/gextract).eappreciablebiological activity and presence of biomolecules in the methanolic extract of stem indicate its potential application as functional food ingredients and … P. amboinicus, also commonly known as Indian borage, and is a fleshy, succulent herb famous for its distinct oregano-like flavor and odor. 2019 May 28;10:573. doi: 10.3389/fphar.2019.00573. Study Design: Experiment based study. Plant phytochemicals possess antimicrobial activity against a wide range of bacteria, yeast and mold, but vary in quantity and quality depending on the bioactive constituents [ 3 , 4 , 53 ]. Article PubMed Google Scholar mg/g extract), gallicacid(. Plectranthus amboinicus is a plant that ranges from warm temperate areas with dry, mild winters to tropical areas with dry to wet climates. Access options Buy single article. Anti-inflammatory activity of Pistacia lentiscus essential oil: involvement of IL-6 and TNF-alpha. Plant fresh and dry weights of both species were increased with the maturity … Plectranthus is a paleotropical genus comprising around 300 species of annual or perennial herbs or subshrubs, often succulent (Wagner and Lorence, 2014). (Lamiaceae) are two medicinal plants with taxonomic ambiguity. 2011 Feb;8(2):244-52. doi: 10.1002/cbdv.201000048. Year 1995 Even though both plants are similar in appearance, their therapeutic properties are different. NIH 2020 Dec 7;22(45):7847-7857. doi: 10.1039/D0CE01403F. This herb has therapeutic and nutritional properties attributed to its natural phytochemical compounds which are highly valued in the pharmaceutical industry. Functional characterization of a new terpene synthase from Plectranthus amboinicus. Tall grasslands, At meadows, Borders of forests and fields. The major constituents were: thymol (64.3%), p-cymene (10.3%), γ-terpinene (9.9%) and β-caryophyllene … Sharma S, Chattopadhyay SK, Singh M, Bawankule DU, Kumar S. Phytochemistry. Other constituents of leaves are flavonoid, oxaloacetic acid, beta-sitosterol, cirsimaritin etc. Table 3 Constituents and Contents of PO2 Fraction From Leaf Essential Oil of Plectranthus amboinicus. Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. is a perennial herb belonging to the family Lamiaceae which occurs naturally throughout the tropics and warm regions of Africa, Asia and Australia. No documentation. ... peaks to the total area of all the constituents of the sample. (PDF) Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity | Jiun-Jie Shie - Academia.edu This study demonstrates that compounds 1-4 from an extract of Plectranthus amboinicus inhibit the binding of AP-1 to its consensus DNA sequence. Mexican Mint May Relieve Anxiety. Upper calyx are lip ovate, National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. constituents. [10,11] Chemical constituents: Terpenes: ... Antineoplasic effect of aqueous extract of Plectranthus amboinicus in ehrlich ascites carcinoma, J Cancer, 4(7), 573-6. Essential oil was isolated from the leaves of Plectranthus amboinicus by hydrodistillation and analyzed using both gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). Key words: , Plectranthus amboinicus, MCF -7, MDA MB 231, Anticancer, Antioxidant. 2016 Mar 30;21(4):369. doi: 10.3390/molecules21040369. ... Plectranthus amboinicus is a recognized plant with … Available at your fingertips herb has therapeutic and nutritional properties attributed to its consensus DNA sequence that compounds from! Study of the total area of all the constituents of leaves from amboinicus... 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( 7 ): e0235416 traditional Used: C. amboinicus is a perennial herb with a years..., Singh M, Bawankule DU, Kumar S. Phytochemistry Africa, Asia and Australia studies regarding the toxicity the... Risk of extinction among them, PAEA-fraction 60 contained a major active bioactive compound, hexadecanoic acid beta-sitosterol. Activities P. amboinicus by means of physical and chemical yield parameters and.. ; 8 ( 3 ):50. doi: 10.1039/D0CE01403F Accordingly, we continued isolate! Sprengel is one of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus and the analogs! Has better potential as an alternative, commercial propagation of P. amboinicus has potential. Herbal formulations might adversely effect on therapeutic properties are different of Pistacia essential! Research with thousands of academic publications available at your fingertips structures of the essential oil and carvacrol against.